PIMISA Search Software for Rapid, Confident Identification of Compounds by DART-MS
PIMISA (Primary Ion Middle Ion Structural Analysis) is our software designed to operate together with the DART-equipped Waters ACQUITY® QDa detector. Using multiple ion fragmentation conditions for each analyte, the software matches a set of spectra against the drug spectral library developed in collaboration with Cayman Chemical, a leading supplier of standard reference materials for forensic laboratories. The user interface features a simple red/green readout to confirm the identity of the compounds.
Features of PIMISA Include:
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Automated post data acquisition analysis
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Provides a simple red light, green light visual display of results
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High confidence identifications of targeted and untargeted compounds
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Create custom DART-MS libraries
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Supplied with a library with over 1000 drug compounds including the most recent emerging drugs
Simple Red/Green Light Display
Compound identification results can be displayed in a red/green light manner to quickly determine whether something passes or fails inspection.
Spectral Interpretation Display
PIMISA also provides a more comprehensive view of the results featuring:
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Total Ion Chromatogram (TIC)
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Reconstructed Ion Chromatogram (RIC)
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Detected hits and their match score
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Mass spectral comparison between sample spectra and library spectra
Application
Swab and Detect with PIMISA
The industry-standard swab sampling allows for surfaces, powders or liquids to be analyzed. The swab is inserted into our thermal desorber (TD), desorbed with heat, and analyzed in seconds by DART-MS. The spectra are then automatically interrogated for a match against the spectral database. The simplicity of the method as well as the straightforward user interface decreases the need for extensive training, allowing the platform to be utilized in a wide range of laboratory environments.
Watch the video below to see how it all works.